乙型肝炎发病趋势分析.docVIP

乙型肝炎发病趋势分析 分析连云港市乙肝发病趋势，为制订科学防治对策提供依据。方法 用Epi info 3.3.2软件对1997-2008年乙肝报告发病数据进行描述性流行病学分析。结果 12年间共报告乙肝病例9483例，报告发病率从1997的24.69/10万下降到2008年的9.86/10万，下降了60.1%，趋势检验有统计学意义(X2trend =78.00，P0.01；其中15岁以下儿童以下乙肝报告发病率由1997的12.45/10万，下降到2008年的0.57/10万，下降了95.4%。乙肝报告发病率高发的新浦区和连云区分别下降了92.7%、80.5%，赣榆县下降了17.2%。55.1%的病例是农民，12.6%是学生，散居儿童（1.2%）多于幼托儿童（0.3%），商业服务人员仅占1.3%。乙肝疫苗调查接种率（除2001年外）均在90%以上。急性乙肝报告病例诊断率逐年提高，由2006的17.1%上升到2008的59.2%；未分类逐年下降，由2006的70.0%下降到2008年的15.5%。结论 该市乙肝发病逐年呈现下降趋势，在提高新生儿出生后首针接种及时率同时，应加强农村人群和重点人群的乙肝免疫工作，确保实现《2006－2010年全国乙型病毒性肝炎防治规划》的目标。 Lianyunggang Municipal Center for Disease Control and Prevention, Lianyungang 222003, Jiangsu Province, China Abstract Objective To analyze the incidence trend of hepatitis B in Lianyungang from 1997 to 2008 and provide scientific evidence for hepatitis B prevention and control. Methods Descriptive epidemiological analysis on the incidence data of hepatitis B in Lianyungang during this period were conducted by using Epi info 3.3.2. Results A total of 9483 cases of hepatitis B were reported from 1997 to 2008, the incidence was 24.69/100 000 in 1997, and 9.86/100 000 in 2008, which declined by 60.1%, the difference was significance(X2trend=78.00，P0.01) The incidence among children aged ＜15 years was 12.45/100 000 in 1997 and 0.57/100 000 in 2008, which declined by 95.4%. The incidence in Xinpu and Lianyun districts declined by 92.7%, 80.5% respectively, and by 17.2% in Ganyu county. Up to 55.1% of the cases were farmers, 12.6% were students, 1.2% were the children living separately, 0.3% were the children in child care settings and 1.3% were the people engaged in commercial service. The vaccination rates of hepatitis B vaccine were all over 90% (86.6% in 2001). The proportion of acute hepatitis B cases increased from 17.1% in 2006 to 59.2% in 2008 and the proportion of unclassified hepatitis B cases declined from 70.0% in 2006 to 15.5% in 2008. Conclusion The incidence of hepatitis B declined in Lianyungang during 1997-2008. It is ne