外文资料A Case of Successful Pregnancy and Delivery after Brain Metastasis of Choriocarcinoma.pdfVIP

Asia-Oceania J. Obstet. Gynaecol. Vol. 19, No. I : 29-35 1993 A Case of Successful Pregnancy and Delivery after Brain Metastasis of Choriocarcinoma Hideo Yokota, Yoshiya Mabuchi, Taro Hosomichi, Masanori Kimura, Hideaki Imai, and Kenji Sutou Department of Obstetrics and Gynecology, WakayamaRosai Hospital, Wakayama,Japan Abstract This is report regarding a 28-year-old woman who conceived and delivered a healthy child following treatment for brain metastasis of choriocarcinoma in 1980 and a pro- longed postoperative disease-free period. The patient had delivered a hydatidiform mole. Eight months afterwards she was admitted to our hospital with occipital pain, vomiting and stupor, and upon C T examination was found to have a brain tumor. The surgically removed tumor was pathologically diagnosed as choriocarcinoma. Postoperative methotrexate chemotherapy rapidly lowered the preoperative urinary human chorionic gonadotrophin (19 IUImZ), and allowed restoration of the preoper- ative LH level, consciousness, ambulation, and manifest ovulation. Occasional mild cramps were received by continuous use of anticonvulsants which did not affect her daily life. Four and one-half years postoperatively she conceived, and had a healthy boy weighing 2,294g at the 39th week of gestation in June 1985. Both mother and baby have been doing well for 7 postpartum years. Key words: choriocarcinoma, brain metastasis, pregnancy, delivery Introduction moved, received MTX, and had a healthy child after a 4-year disease-free period. Brain metastasis of choriocarc