过氧化氢选择性氧化硫醚的研究进展有机化学.pdfVIP

DOI: 10.6023/cjoc201310019 综述与进展 有机化学 Chinese Journal of Organic Chemistry REVIEW 过氧化氢选择性氧化硫醚的研究进展 刘课艳 偶 辉 石先莹* 董雪芬 马文娟 魏俊发* (陕西师范大学化学化工学院 陕西省大分子科学重点实验室 西安 710062) 摘要 亚砜和砜类化合物具有广谱生物活性而有广泛的应用前景, 同时作为有机合成的重要中间体广泛应用于碳-碳 键形成、分子重组反应中. 硫醚直接氧化是制备亚砜和砜的主要方法之一. 在众多关于硫醚选择性氧化反应的研究中, 过氧化氢作为清洁氧化剂备受关注. 鉴于此, 就过氧化氢选择性氧化硫醚反应中的重要金属催化体系和一些非金属催 化体系的研究状况作一综述, 简要介绍各类催化氧化体系的催化效果. 关键词 催化氧化; 硫醚; 砜; 亚砜; 过氧化氢 Recent Progress in the Selective Oxidation of Sulfides with Hydrogen Peroxide Liu, Keyan Ou, Hui Shi, Xianying* Dong, Xuefen Ma, Wenjuan Wei, Junfa* (Key Laboratory for Macromolecular Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xian 710062 ) Abstract Sulfoxides and sulfones have broad applications in pharmaceutical agents and pesticide due to their biologically activities and they are important synthetic intermediates in C—C bond formation and various molecular rearrangements. The selective oxidation of sulfides is a straightforward and frequently used method to obtain sulfoxides and sulfones. Among vari- ous oxidizing agents, hydrogen peroxide as benign oxidant has attracted organic chemists’ attention for a long time. This re- view summarizes the recent and important catalytic systems of metal and nonmetal in this area. The catalytic effect of different catalytic systems is briefly discussed herein. Keywords catalytic oxidation; sulfides; sulfones; sulfoxides; hydrogen peroxide 亚砜和砜类化合物具有广谱生物活性而有广泛的 是实现清洁生产的关键. 其