Comparative Analysis of the Testis and Ovary Transcriptomes in Zebrafish by Combining Experimental and Computational Tools.pdfVIP

Comparative and Functional Genomics Comp Funct Genom 2004; 5: 403–418. Published online in Wiley InterScience (). DOI: 10.1002/cfg.418 Research Article Comparative analysis of the testis and ovary transcriptomes in zebrafish by combining experimental and computational tools 1# 2,3# 1,4 3 1 1 1 Yang Li , Jer Ming Chia , Richard Bartfai , Alan Christoffels , Gen Hua Yue , Ke Ding , Mei Yin Ho , 1 5 1,4 James A. Hill , Elia Stupka * and Laszlo Orban * 1Reproductive Genomics Group, Temasek Lifesciences Laboratory, Singapore 2 Genome Institute of Singapore, Singapore 3Institute of Molecular and Cell Biology, Singapore 4 Department of Biological Sciences, National University of Singapore, Singapore 5 Computational Biology, Temasek Lifesciences Laboratory, Singapore *Correspondence to: Abstract Laszlo Orban, Reproductive Genomics Group, Temasek Studies on the zebrafish model have contributed to our understanding of several Lifesciences Laboratory, important developmental processes, especially those that can be easily studied in the Singapore. embryo. However, our knowledge on late events such as gonad differentiation in the E-mail: laszlo@.sg zebrafish is still limited. Here we provide an analysis on the gene sets expressed in the adult zebrafish testis and ovary in an attempt to identify genes with potential Elia Stupka, Computational role in (zebra)fish gonad development and function. We produced 10 533 expressed Biology Group, Temasek Lifesciences Laboratory,