Molecular chaperones are nanomachines that catalytically unfold misfolded and alternatively folded proteins.PDFVIP

Cell. Mol. Life Sci. (2014) 71:3311–3325 DOI 10.1007/s00018-014-1627-y Cellular and Molecular Life Sciences RevIew Molecular chaperones are nanomachines that catalytically unfold misfolded and alternatively folded proteins Rayees U. H. Mattoo · Pierre Goloubinoff Received: 19 December 2013 / Revised: 4 April 2014 / Accepted: 7 April 2014 / Published online: 24 April 2014 © The Author(s) 2014. This article is published with open access at S Abstract By virtue of their general ability to bind (hold) Introductio