Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism.PDFVIP

REVIEW Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism RAFAL TOMECKI1,2 and ANDRZEJ DZIEMBOWSKI1,2 1Institute of Biochemistry and Biophysics, Polish Academy of Sciences, University of Warsaw, 02-106 Warsaw, Poland 2 Department of Genetics and Biotechnology, Faculty of Biology, University of Warsaw, 02-926 Warsaw, Poland ABSTRACT For a long time it has been assumed that the decay of RNA in eukaryotes is mainly carried out by exoribonucleases, which is in contrast to bacteria, where endoribonucleases are well documented to initiate RNA degrad