Nuclear–Cytoplasmic Shuttling of the Focal Contact Protein, Zyxin A Potential Mechanism for Communication between Sites of Cell Adhesion and the Nucleus.PDFVIP

Nuclear–Cytoplasmic Shuttling of the Focal Contact Protein, Zyxin: A Potential Mechanism for Communication between Sites of Cell Adhesion and the Nucleus David A. Nix and Mary C. Beckerle Department of Biology, University of Utah, Salt Lake City, Utah 84112 Abstract. Integrin-dependent cell adhesion to specific abundance phosphoprotein that accumulates with inte- extracellular matrix molecules has been demonstrated grins at sites of cell–substratum attachment. Here we to trigger dramatic changes in gene expression that can