苯佐卡因合成研究 材料.docVIP

苯佐卡因的合成的研究 学 生 姓 名 指 导 教 师 专 业 学 院 年月日摘　　要 Abstract Benzocaine is an important medicinal intermediate products of Orthoform，Orthocaine and Procaine，and is also one of local anesthetics.The preparation of Benzocaine by esterification and reduction from 4-Nitrobenzoic acid and Ethanol has been intensively studied. The synthesis of p-Nitro-ethylbenzoate by three methods.p-Nitro-ethylbenzoate was synthesized by conventional heating method,using p-toluene sulfonic acid as catalyst.The reaction time was 2.