DIC-弥漫性血管内凝血.ppt

DIC的诊断与治疗 北京协和医院血液科 DIC的定义 Disseminated Intravascular Coagulation DIC是一种发生于多种疾病或特殊病理状态下，人体凝血系统被激活而引起中小血管内弥漫性微血栓形成及继发性纤溶亢进的综合征。 由于DIC发展过程中出现不同程度的血小板和凝血因子水平消耗性减少，也称之为“消耗性凝血病”或“消耗性血栓出血性疾病”。 Clinical conditions associated with DIC 1. Sepsis/Severe infection --- -------- 44.6% 2. Malignancy ------------------------- 20.7% Solid tumors 6.9%，AL 13.8%. Occurrence in APL 37~65%. 3. Obstetrical calamities ------------ 13.4% Amniotic fluid embolism, Abruptio placentae, Dead fetus 4. Trauma / Surgery ----------------- 7.4% 5. Severe hepatic failure ------------ 7.4% 6. Vascular abnormalities Kasabac