不同加工工艺对医用镁锌钇钕合金显微组织的影响大学本科毕业设计.docVIP

不同加工工艺对医用镁锌钇钕合金显微组织的影响 摘 要 随着生物医用可降解材料研究的不断深入与发展，由于镁基合金具有良好的生物相容性、生物可降解性以及力学性能，逐渐引起了人们的广泛关注。镁是人体内必需的微量金属元素，具有良好的生物相容性和生物可降解性。随着血管内治疗技术的发展，血管内支架植入术已经成为了治疗心血管疾病最有效的方法之一。常用的血管支架材料包括了不锈钢、镍钛、钴铬合金等生物惰性材料，这些支架材料作为异物虽然能够长期存在于人体内，但会引起内膜的过度增生，造成15% ～ 30% 的术后再狭窄。除了术后再狭窄，这些不可降解的惰性金属支架还能够产生内皮功能紊乱、凝血、慢性炎症、血管与支架机械性能不匹配等生物相容性问题，这在一定程度上限制了金属血管支架在临床中的应用。而本文主要通过对医用镁锌钇钕合金的研究，采取不同的加工工艺以获得相应的结果，并通过相应的实验获得了下面相应的结果，实验表明： （1）普通凝固态 Mg-Zn-Y -Nd 合金经过三种不同挤压工艺挤压后，合金的晶粒发生显著细化。 （2）挤压后合金结构相的组成和分布发生明显的变化。 （3）挤压工艺在细化晶粒的同时会降低合金的耐腐蚀性能。 关键字：镁锌钇钕合金，晶粒，耐腐蚀性 Effect of ifferent Processing Technology for Medical Mg-Zn Alloy Microstructure Neodymium Yttrium Author: Abstract With the deepening and development of bio-degradable materials for medical research, because magnesium-based alloys have good biocompatibility, biodegradability and mechanical properties, gradually attracted extensive attention .Commonly used stent materials include stainless steel, nickel, titanium, cobalt-chromium alloys and other biologically inert materials, these scaffolds as though the long-term presence of foreign substances in the human body, but can cause endometrial hyperplasia, resulting in a 15% to 30% of patients restenosis. Restenosis after addition of these inert non-biodegradable metal stent can also produce endothelial dysfunction, coagulation, chronic inflammation, vascular stents and other mechanical properties mismatch problem of biocompatibility, the metal stent which limits to a certain extent in the clinical applications. The paper mainly through the study of medical magnesium-zinc alloy of neodymium, yttrium, take a different process to obtain the corresponding results and the corresponding results obtained by following the appropriate experiments showed that: (1) Ordinary solidified Mg-Zn-Y-Nd alloy extrusion process after three different extrusion, alloy grains occur significantly refined. (2) The composition and distribution of the extruded alloy structural phase change dramatically. (3) Extrusion process