多西环素胶囊BP2003.docVIP

多西环素胶囊BP2003 Doxycycline Capsules Definition Doxycycline capsules contain doxycycline hyclate. The capsules comply with the requirements stated under Capsules and with the following requirements. Content of anhydrous doxycycline, C22H24N2O8 95.0 to 105.0% of the stated amount. Identification A. Carry out the method for thin-layer chromatography, Appendix III A, using silica gel H as the coating substance and a mixture of 6 volumes of water , 35 volumes of methanol and 59 volumes of dichloromethane as the mobile phase. Spray the plate evenly with a 10% w/v solution of disodium edetate th