The history of detoxication of deoxynivalenol (DON).pptxVIP

The history of detoxication of deoxynivalenol (DON) Liang Yafeng Vomitoxin, also known as deoxynivalenol (DON), is a type B trichothecene, an epoxy-sesquiterpeneoid. This mycotoxin occurs predominantly in grains such as wheat, barley, oats, rye, and maize, and less often in rice, sorghum, and triticale. F. graminearum produce mainly DON, NIV and their derivatives DON is a strong protein inhibitor. The putative site of action of this molecule has been theorized to be the 60S ribosomal protein L3 (RPL3) Inhibition of protein synthesis following exposure to DON causes the brain to increase its up