PediatricandCongenitalHeartDiseaseCommon.ppt

Tetralogy of Fallot PS is the most important Tetralogy of Fallot Pathophysiology of TOF Kawasaki Disease Epidemiology Most common in Japan Most likely to occur during the winter and spring Male to female ratio is 1.5 ：1 80% of affected patients are younger than age 5 years The mortality rate is around 0.17% Etiology remain unclear mutiple agents Including Staphylococus, Streptococcus, Rickettsia viruses and environmental chemicals A infectious etiology is thought to be likely Pathogenesis Affecting small- and medium-sized arteries Multiple organ system are involved Cardiovascular involv