《年产300t红霉素生产工厂的初步设计 》.doc

300 t/a 红霉素生产工厂的初步设计 专业：生物工程 作者：傅向科 指导老师：李会东 (湖南科技大学 生命科学学院 0709030226) 摘要Major: Biology Engineering Author: Fu Xiangke Supervisor: Li Huidong (School of Life Sciences Hunan University of Science and Technology 0709030226) Abstract：The Fermentation Engineering and Equipment Course Design can play the connecting role between the preceding and the following in the practice teaching, and lay a good foundation for the students to work in the factory after graduation. This subject is an initial technological design for Erythromycin with year output of 300 ton.According to the requirement,the process of erythromycin production and the calculation of the mass balance and heat quantity balance are completed. In this subject , all of theprocesses are expounded in detail. All the contents are based on the academic calculations .we refer to the practical designes in companies and make our best to approach to the practice. it mainly includes the production craft each kind of target,the equipment chooses the shapedesign calculation,material of the graduated arm of a steelyard calculation,the water,the electricity,the steam estimate as well as the flow chart design.This designachievement mainly uses the form for the entire factory totalfloor-plan(1),flowchat(1),equipment general arrangement(1),and compilation particular data instruction booklet.. Key word: Erythromycin; Process; Design 前 言 毕业设计是普通高校本科教育的最后一个环节，也是必不可少的一个环节，是理论知识和实际应用相结合的重要措施。红霉素的需求在日益扩大，因此作为即将走向工作岗位的毕业生对其工艺过程了解是很有必要的。本设计为年产量300t红霉素的初步工艺设计，其生产方法是发酵法，参照大量红霉素生产工艺和化工设计的有关资料。 本设计分别对红霉素的结构、理化性质、作用机理、工艺流程等作了相应的阐述，并对有关的物料和热量也作了相应的衡算，以及对标准设备的选型和计算，还对工艺指标、安全问题和环境保护等都作了详细的阐述。其中对生产中的补料问题做出了解决，采用了国内先进技术——自动补料系统。本设计以理论设计为依据，以实际生产为参考，力求接近实际，切合实际。 在本次设计过程中，自始自终得到李会东老师的悉心指导和同组同学的热心帮助，在此表示衷心的感谢！ 由于本人水平有限，设计经验不足，设计中难免存在疏漏和不妥之处，敬请各位老师批评指正。 设计人：傅向科 2011年5月30日 1 绪论 1.1 红霉