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清华大学2005至2006年生物化学期末考试试题
清华大学本科生考试试题专用纸?(A)
考试课程??Biochemistry II????2005?年??1?月?15??日
说明:1.?第1-40题为选择题,每题2分,答案可能是一个或多个,请将??????
?????????正确答案填在适当的横线处;
2.?第41-44题为问答题,每题的分数标在了题目后面,请将答案写
???在答题纸上;
3.?本卷满分为100。
1. Which compound links glycolysis, nucleotide synthesis, and glycogen synthesis?
A.牋牋acetyl-CoA
B.牋牋爋xaloacetate
C.牋牋燾itrate
D.牋牋glucose 6-phosphate
E.牋牋爂lycerol 3-phosphate
INCLUDEPICTURE \d /upfiles/201003/20100313101350903.gif \* MERGEFORMATINET Answer(s):牋D
2. You have discovered a compoun d that inhibits fumarase. How many moles of ATP would you expect to be generated from one mole of acetyl-CoA in the presence of this inhibitor?
A.牋牋5
B.牋牋?
C.牋牋?.5
D.牋牋7.5
E.牋牋燦o ATP would form under these conditions.
INCLUDEPICTURE \d /upfiles/201003/20100313101350903.gif \* MERGEFORMATINET Answer(s):牋D
3. Indicate which of the followi ng events can occur during the processing of eukaryotic mRNA transcripts.
A.牋牋Attachment of a poly (A) tail to the 5?end of the transcript.
B.牋牋燤ethylation of all G residues.
C.牋牋燛xcisions of introns.
D.牋牋Conversion of standard bases to modified bases such as inosine.
E.牋牋燬plicing together of exons.
F.牋牋牋Differential cutting and splicing to produce two different proteins.
INCLUDEPICTURE \d /upfiles/201003/20100313101350903.gif \* MERGEFORMATINET Answer(s):牋CE
4. Although DNA replication has very high fidelity, mutations do occur. Which of the following types of single base-pair mutations would be most likely to be a lethal mutation?牋?A.牋牋substitution
B.牋牋爄nsertion
C.牋牋燿eletion
D.牋牋silent
E.牋牋燘 and C
INCLUDEPICTURE \d /upfiles/201003/20100313101350903.gif \* MERGEFORMATINET Answer(s):牋E
5. Which of the following燾orrec tly燿escribes the nitrogen cycle??A.牋牋Fixation of atmospheric nitrogen by nitrogen-fixing bacteria yields bioavailable nitrate.
B.牋牋燦itrate is reduced to ammonia in a process known as denitrification.
C.牋牋燘iological nitrogen fixation is carried ou t by a co
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