eNOS基因转染对慢性缺氧性肺动脉高压的影响.docVIP

eNOS基因转染对慢性缺氧性肺动脉高压的影响 作者：周锦，王俊科，张铁铮，金强，张毅男，王凤学 【关键词】 高血压,肺性；基因疗法；一氧化氮合酶；重组,遗传；腺病毒科 Effect of adenovirusmediated human endothelial nitric oxide synthase gene transfer on chronic hypoxic pulmonary hypertension 【Abstract】 AIM: To investigate the effect of adenovirusmediated human endothelial nitric oxide synthase gene transfered to the rat lungs through airway on chronic hypoxic pulmonary hypertension rats and to explore its possible role in CHPH therapy. METHODS: Thirty male Wistar rats were randomly pided into 3 groups. the contr