[370例心包积液住院患者病因.docxVIP

370例心包积液住院患者病因分析吴海东摘要 目的 了解不同性别、年龄阶段的包积液住院患者的病因构成特点。方法 370例确诊为心包积液的住院患者分别按性别分组和按年龄分为少儿组(0～18岁)、青年组(19～39岁)、中年组(40～59岁)、老年组(60～79岁)和高龄老年组(≥80岁)5个年龄段，建立心包积液住院患者临床资料数据库，对比分析各组的病因构成。结果总体上，前6位病因分别为肿瘤（34.9%）、心力衰竭（18.1%）、系统性红斑狼疮（SLE）（10%）、结核（9.5%）、尿毒症（7.3%）和甲状腺功能减退症（6.5%）。不同性别、年龄阶段患者心包积液的病因构成明显不同，男性的肿瘤和结核患者多于女性，而女性的SLE和甲状腺功能减退症患者多于男性患者。心包积液病因中，除青年组以SLE占首位外，其余各组肿瘤均居于首位，在中老组中最多。心力衰竭在老年组（≥60岁）（41/139，29.5%）多于非老年组（＜60岁）（26/231，11.3%） (Χ2=19.47，P0.001)。肺癌是肿瘤性心包积液中最常见的病因(43.4%，56/126)，老年组肺癌占比（55.6%，25/45）最高。结论不同性别、年龄阶段患者心包积液的病因构成不同，随着年龄增长，心包积液患者的病因中肿瘤、心力衰竭所占比例呈上升趋势,在心包积液的诊断和治疗中应当注意上述特点。关键词：心包积液；病因；肿瘤Etiological analysis of 370 in-patients with pericardial effusionWu Haidong1, Lan Weixiong2, Wu Manhui1, Jiang Longyang1, Huang Zitong11.Department of Emergency, Sun-Yat-Sen memorial hospital, Sun-Yat-Sen University; Institute of cardiopulmonary cerebral resuscitation, Sun-Yat-Sen University, Guangzhou 510120, China 2. Huali hospital of Nanhai ShishanAbstract Objective To survey and analyze the pathogenesis of pericardial effusion in different sex and age in-patients. Methods The data of 370 in-patients who were discharged and diagnosed as pericardial effusion were studied retrospectively. The pathogenesis of pericardial effusion were analyzed and compared between male and female or among the five age groups: juvenile group(0～18 years), young group(19～39 years), middle age group(40～59 years), aged group (60～79 years)and existed advanced age group(≥80 years). Results The first six causes of pericardial effusion are tumor(34.9%), heart failure(18.1%), systemic lupus erythematosus (SLE) (10%), tuberculosis(9.5%), uremia(7.3%) and hypothyroidism(6.5%) in all in-patients. The different distribution of pathogenesis exist in different sex and age groups. Tumor and tuberculosis as causes of pericardial effusion are more often in male than in female, but SLE and hypothyroidism are more often in female than in male. Tumor is the first cause of pericardial effusion in age groups except the yo