血脂调整与脑卒中的预防.ppt

血脂调整与脑卒中的预防 复旦大学上海医学院中山医院神经内科 汪 昕 CURE: Clopidogrel in Patients with a Previous Stroke1 上海市城市综合干预中风发病情况(1991-2000) Relationship between lipids and stroke risk Mixed results in trying to identify an association between cholesterol and stroke Most studies measured total cholesterol Did not look at LDL cholesterol Did not distinguish among stroke subtypes Early meta-analyses suggested no relationship More recent studies show an effect for athero-thrombotic strokes 他汀类药物一二级预防历史 缺血性中风 安慰剂 治疗组 降低 一级预防 Woscops 51 46 10%