图优秀培训书.pptVIP

* Figure 10.1 A heteroduplex Crossing over Pairing of homologous chromosomes Figure 10.2 5’ 3’ 3’ 5’ 3’ 5’ 5’ 3’ 5’ 3’ 3’ 5’ 3’ 5’ 5’ 3’ 5’ 3’ 3’ 5’ 3’ 5’ 5’ 3’ Synapsis (Rad51 coated single strand searches its complementary strand) 5’ 3’ 3’ 5’ 3’ 5’ 5’ 3’ 5’ 3’ 3’ 5’ 3’ 5’ 5’ 3’ 5’ 3’ 3’ 5’ 3’ 5’ 5’ 3’ A double strand cut made by enzyme Spo11 Exonuclease, MRX complex and Rad51 5’ 3’ 5’ 3’ Rad51 5’ 3’ Strand invasion and D-loop formation 5’ 3’ DNA repair synthesis Sealing gaps Chromosome A Chromosome B Figure 10.3 Branch migration Figure 10.4 Four cuts are made as indicated by the arrows Mol