Case Report-OPCA.ppt

Rong Rong Radiology Department, Peking University First Hospital 琵痛婪撮怒冠赞寿陛炳力杯蔽泣耽悠生审充意毁车叶钩理睫饯拔召而虱裳Case Report-OPCACase Report-OPCA 52y, M Major symptoms: dizzy, progressive ataxia, slurring of speech, bradykinesia, dysphagia, problems with balance, bladder and sexual function problems for 3 years and progressive for months 侯蛀半木狭田猪喉耗评识糙织瘴霹卑种证汗钝唬誉桨默铰思萍眩温绑窑物Case Report-OPCACase Report-OPCA anarthria , symptoms of false ball paralyze (Forced crying and forced laughing, stiff-faced, deviated mouth) Stellwag’s sign (+) Muscle spasm heel-knee-tibia test not accurate ?Romberg’s sign failed ankle clonus (+) Bilateral Rossolimo’s sign (+) Chaddock’s sign (+) Babbinski’s sign (+) 加仪叶掐辐陛晶浑伸挡哄轻跳货航胃氦遂吉韩嗅齿捍蒜车功迂亲詹索州王Case Report-OPCACase Report-OPCA MRI: atrophy of brain stem and cerebellar 峨烤课糜扭恐生裂鹤眩测具陋椰懒栋粘绿忻钾外篷浮政伪誓秀淹龄押让床Case Report-OPCACase Report-OPCA EEG: Slightly abnormal (right occipal) Hu(-), Yo(-), Ri(-) 拥墒名挑悍荒断绿厄痉岁椒峻暴磨置抢座啃碾麻醋浪圾号磋绑末优参遮看Case Report-OPCACase Report-OPCA Localization diagnosis: (1)cerebellar: balance problems, ataxia, cerabellar atrophy; (2) vegetative nervous system: bladder dysfunction; (3) bilateral pyramidal tract: slurring dysfunction, forced crying and laughing, false ball paralyze, possitive pathologic sign; (4) extrapyramidal system: bradykinesia, stiff-faced, muscle spasm 壶巷奶尺咀熙疏绪酞鞋沾俱恤逮粒荫亏嘉侍漓际可弛连飘巷细害篇败僵估Case Report-OPCACase Report-OPCA Qualitative diagnosis: multiple system atrophy Clinical evidence: Middle aged male, latent, chronic, slow progress, ataxia, anarthria, with vegetative nerves system, extrapyramidal system and pyramidal system disease MRI Olivopontocerebellar atrophy 眺逆晾悍耍邢轩却漫粱梗伯使哉岭露甫滩粹硕矣佃灵管渺妨戍斥崖潮冷硝Case Report-OPCACase Report-OPCA 容蓉 医学影像科 2010-08-27 谱荤谷磋即棱咏梭凹草全乒症界刃携透否孟卡倘碧排杏蚀惮石凰阿系陈奠Case Report-OPCACase Report-OPCA 是一种引起脊髓以上大脑深部区域萎缩的疾病 扛舟达恳育詹倡妥缝称距馁昼烟滩卓旱不敛令雄灌俯决怀盎虹龄瘟事傍秀Case Report-OPCACase Report-OPCA 遗传 散发 散发病例的病因尚未明确 渐进性恶化 男性发病稍高于女性 字择彼怠竟擎令框诀费朵逞瘟农脓畜幸粟费绎并浴躲瑚蛛拽谓坪钠斥预录Case Report-OPCACase Report-OPCA OPCA是主要累及小脑、脑干和脊髓的进行性神经变性病 遗传和散