renal failure.pptVIP

Excretion filtration, resorption and secretion, to maintain the balance in water, electrolytes, acid and alkali Endocrine renin, prostaglandins, erythropoietin, 1,25 (OH)2VitD3 Inactivation PTH, pepsin Classification of Renal Failure Acute Renal Failure — conception ARF — causes and classification Prerenal hypovolemia, reduced cardiac output or vascular obstruction Intrarenal vasculopathies, glomerulonephritis, tubulointerstitial nephropathies, acute tubular necrosis Postrenal obstruction in bladder neck, intra- and extra-urethral ARF — characteristics  Pathogenesis (4) Pathogenesis (5) Renal vascular system Alterations of Metabolism and Functions Alterations of Metabolism and Functions Alterations of Metabolism and functions Alterations of Metabolism and Functions Oliguria phase Alterations of Metabolism and Functions Oliguria phase Alterations of Metabolism and Functions 2. Diuretic phase (urine 400ml/day) Alterations of Metabolism and Functions Alterations of Metabolism and Functions Discussion: Discussion 5. Is diuresis phase safe to the patient? 6. Why did they use mannitol? Insulin plus glucose? And magnesium sulfate in treatment？ 7. Did the patient suffer from functional or parenchyma ARF? 8. Why the patients with non-oliguria type ARF show disturbance of internal homeostasis when they do not have oliguria？ Chronic Renal Failure- Conception It is a process that the kidneys are affected progressively by the insults and thus an irreversible loss of large numbers of functioning nephrons occurs The disorders in both excretion and endocrine are shown; Internal environmental disturbance and may have multifunctional deregulation Pathogenesis (1) Pathogenesis (3) Alterations of Metabolism and Functions 2.Changes in homeostasis (1) Azotemia (2) Acidosis (3) Disorders in electrolytes met