郑州大学有机化学10醇醚课稿.ppt

(±) Ring Opening in Acid The reaction is SN1 like 10.9 Preparation 10.9.1 Acid-Catalyzed Intermolecular Dehydration of Alcohols If temperature is too high, alkene forms. 1o alcohols—SN2 2o and 3o alcohols—E1 10.9.2 The Williamson Synthesis of Ethers SN2 L= Br, I, OSO2R’’, OSO2OR’’ R’ ——CH3, primary or secondary alkyl SN1 二芳基醚用Ullmann反应合成 10.9.3 Acid-catalyzed Addition of Alcohols to Alkenes protecting group 乙烯基醚的合成 10.9.4 Alkoxymercuration of Alkenes (烯的烷氧汞化) 10.9.5 Preparation of Epoxides (环氧化合物的制备) Epoxidation of alkenes Base-promoted ring closure of vicinal halohydrins (碱促进下β-卤代醇的环合)