非小细胞肺癌的标靶治疗课件.pptVIP

Targeted Therapy in Non-Small-Cell Lung Cancer 非小細胞肺癌的標靶治療 NSCLC- Survival by Stage NSCLC Treatment The “First Generation” Agents Methotrexate, cyclophosphamide, vincristine, and doxorubicin—were essentially inactive in NSCLC, despite being widely used in the 1970s and 1980s. The “2nd Generation” Agents Cisplatin, ifosfamide, mitomycin, vindesine, vinblastine, and etoposide in late 1980. The “3rd Generation” Agents Paclitaxel, docetaxel, gemcitabine and vinorelbine emerged in the chemotherapy of NSCLC In the middle 1990s. Cisplatin-based doublets are the mainstay of chemotherapy for advanc