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1 Sleep We all know that the normal human daily cycle of activity1 is of some 7-8 hours sleep alternating with some 16-17 hours wakefulness and that, broadly speaking, the sleep normally coincides with the hours of darkness2. Our present concern is with how easily and to what extent this cycle can be modified. The question is no mere academic one.3 The case, for example, with which people can change from working in the day to working at night is a question of growing importance in industry where automation calls insistently for round-the-clock working of machines. It normally takes from f