University of Utah,.pdf

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c s N m JIrina Ionescu Department of Bioengineering, and Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, UT 84112 James E. Guilkey Department of Mechanical Engineering, University of Utah, Salt Lake City, UT 84112 Martin Berzins Robert M. Kirby Scientific Computing and Imaging Institute, School of Computing, University of Utah, Salt Lake City, UT 84112 Jeffrey A. Weiss1 Department of Bioengineering, and Scientific Computing and Imaging Institute, University of Utah, 50 South Central Campus Drive, Room 2480, Salt Lake City, Utah 84112-9202 e-mail: jeff.weiss@ Simulation of Soft Tissue Failure Using the Material Point Method Understanding the factors that control the extent of tissue damage as a result of material failure in soft tissues may provide means to improve diagnosis and treatment of soft tissue injuries. The objective of this research was to develop and test a computational frame- work for the study of the failure of anisotropic soft tissues subjected to finite deformation. An anisotropic constitutive model incorporating strain-based failure criteria was imple- mented in an existing computational solid mechanics software based on the material point method (MPM), a quasi-meshless particle method for simulations in computational mechanics. The constitutive model and the strain-based failure formulations were tested using simulations of simple shear and tensile mechanical tests. The model was then applied to investigate a scenario of a penetrating injury: a low-speed projectile was released through a myocardial material slab. Sensitivity studies were performed to es- tablish the necessary grid resolution and time-step size. Results of the simple shear and tensile test simulations demonstrated the correct implementation of the constitutive model and the influence of both fiber family and matrix failure on predictions of overall tissue failure. The slab penetration simulations produced p