Acrosin, the peculiar sperm-specific serine protease.pdfVIP

Hum Genet (1991) 87:635-641 9 Springer-Verlag 1991 Review article Acrosin, the peculiar sperm-specific serine protease Uwe Klemm I, Werner Miiller-Esterl 2, and Wolfgang Engel 1 l Institut for Humangenetik der Universitfit, Gosslerstrasse 12d, W-3400 G6ttingen, Federal Republic of Germany 2Institut for Physiologische Chemie und Pathobiochemie der Universit~it, Duesbergweg 6, W-6500 Mainz, Federal Republic of Germany Received January 8, 1991 / Revised April 10, 1991 Summary. The sperm enzyme acrosin has long been known as one of the key enzymes in the mammalian fer- tilization proces