结直肠癌的TNM分期标准2002.docVIP

AJCC关于结直肠癌的TNM分期标准（2002） American Joint Committee on Cancer (AJCC) TNM Staging System for Colorectal Cancer* Primary Tumor (T) TX Primary tumor cannot be assessed T0 No evidence of primary tumor Tis Carcinoma in situ: intraepithelial or invasion of lamina propria T1 Tumor invades submucosa T2 Tumor invades muscularis propria T3 Tumor invades through the muscularis propria into the subserosa, or into nonperitonealized pericolic or perirectal tissues T4 Tumor directly invades other organs or structures, and/or perforates visceral peritoneum Regional Lymph Nodes (N) NX Regional lymph nodes cannot be assessed N0 No regional lymph node metastasis N1 Metastasis in 1 to 3 regional lymph nodes N2 Metastasis in 4 or more regional lymph nodes Distant Metastasis (M) MX Distant metastasis cannot be assessed M0 No distant metastasis M1 Distant metastasis Stage Grouping Stage T N M Dukes 0 Tis N0 M0 - I T1 N0 M0 A T2 N0 M0 A IIA T3 N0 M0 B IIB T4 N0 M0 B IIIA T1-T2 N1 M0 C IIIB T3-T4 N1 M0 C IIIC Any T N2 M0 C IV Any T Any N M1 D Histologic Grade (G) GX Grade cannot be assessed G1 Well differentiated G2 Moderately differentiated G3 Poorly differentiatied G4 Undifferentiated 功能状态评分（Performance Status Score） ECOG/Zubrod ScorePerformance Status0Asymptomatic1Symptomatic, fully ambulatory2Symptomatic,in bed 50% of the day3Symptomatic,in bed 50% of the day but not bedridden4Bedridden5Dead