罗哌卡因用于妊高症患者硬膜外麻醉的临床观察1.docVIP

罗哌卡因用于妊高症患者硬膜外麻醉的临床观察 程 峰 安徽医科大学附属六安医院麻醉科 安徽 六安237005 摘要 目的 探讨0.75%罗哌卡因用于妊高症患者硬膜外麻醉的效果。方法 选择妊高症患者60例，采用0.75%罗哌卡因与2%利多卡因行硬膜外麻醉。观察麻醉起效时间、镇痛肌松效果、术中并发症及生命指征变化。结果 两组的麻醉阻滞完全时间、婴儿娩出后的APgar 评分本观察中也没有明显差异(P0.05)。实验组的镇痛肌松效果的优与差和对照组相比有明显差异(P0.05)。实验组的低血压和恶心、呕吐均低于对照组(P0.05)。两组患者在麻醉后20min、30min时MAP与麻醉前相比都有显著变化(P0.05)，并且MAP的变化组间比较有统计学意义P0.05。实验组的HR变化不大，对照组的HR在20min、30min时的变化与麻醉前比较有显著差异(P0.05)；两组间的HR变化在20min、30min时比较有统计学意义P0.05。结论 罗哌卡因???于妊高症患者硬膜外麻醉下行剖宫产术有效、安全。 关键词 罗哌卡因；妊高症；硬膜外麻醉 Ropivacaine for epidural anesthesia in patients with pregnancy-induced hypertension: a clinical observation Cheng feng Anhui medical university hospital affiliated lu’an anhui lu’an 237005 Abstract:Objective Discussion 0.75% with ropivacaine in patients with pregnancy-induced hypertension effect of epidural anesthesia.Methods Selection of maternal 60 cases with pregnancy-induced hypertension, 0.75% of ropivacaine with lidocaine hydrochloride 2% epidural anesthesia. Observation of onset of anaesthesia, analgesia and muscle relaxant effects, APgar score and intraoperative complications in infants and indication changes lives. Results Two groups of patients after anesthesia in 20 min, 30 min MAP when compared with before anesthesia are a significant change (P 0.05), and the change of the MAP between groups more statistical significance P 0.05. Two group of HR changes when 20min, 30min the comparison has statistics significance P0.05; Experimental groups HR change is not big, control groups HR in time 20min, before the 30min change and the anaesthesia the comparison has the remarkable difference (P0.05). Conclusions Ropivacaine for epidural anesthesia on pregnancy-induced hypertension syndrome women effective, safe caesarean. Key words: Ropivacaine; pregnancy-induced hypertension; epidural anesthesia 妊娠高血压综合征是妊娠期特有的疾病，发生于妊娠20 周以后，发病率约为10.32％。 由于病因不明，无有效的预防方法，且重度妊高征对母婴危害极大，是孕产妇和围生儿死亡的主要原因之一［1］。罗哌卡因是一种新型长效酰胺类局麻药，近年来的临床应用研究发现其能够安全、有效地应用于许多临床麻醉中。[3-10]本文比较我院2009年~ 2011年期间收治的妊高症患者应用0.75%罗哌卡因与2%利多卡