40例类风湿关节炎患者中医证候要素分析.pdf

第 31 卷第 21 期 第 三 军 医 大 学 学 报 Vol. 31，No. 21 2009 年 11 月 ACTA ACADEMIAE MEDICINAE MILITARIS TERTIAE Nov. 2009 2103 文章编号? 1000-5404? 2009? 21-2103-03 论著 401 例类风湿关节炎患者中医证候要素分析 ， ， ， 李 静 柏干苹 王 勇 方勇飞 ? 第三军医大学西南医院中西医结合科，重庆 400038? 摘 要? 目的 对类风湿关节炎? rheumatoid arthritis，RA? 患者的中医症状及相关资料进行统计分析，探讨其结果与 相关指标间的关系。为 RA 的证候学研究及临床治疗提供依据。方法 采用临床流行病学的方法设计调查问卷，收集分 析资料，利用多元统计方法进行数据统计。结果 401 例 RA 患者中医症状可归纳为寒、热、虚 3 个公因子，可分为寒证、 热证、虚证、寒热错杂证、虚寒证、虚热证 6 类证候。差异性统计分析结果提示健康问卷调查评分、血小板、类风湿因子、抗 角蛋白抗体在各证候间有统计学差异? P 0. 05? 。结论 重庆地区 RA 患者中以寒热错杂证多见，热证多见于疾病活动 期，而稳定期多见寒证，RA 疾病活动性与中医证候相关。 关键词? 类风湿关节炎? 中医证候? 多元统计 中图法分类号? R195. 4? R241. 4? R593. 21 文献标识码? A Analysis on traditional Chinese medicine syndroms of 401 rheumatoid arthritis patients ， ， ， LI Jing BAI Gan-ping WANG Yong FANG Yong-fei ? Department of Traditional Chinese Medicine，Southwest Hospital，Third Military Medical University，Chongqing 400038，China? Abstract? Objective To investigate the traditional Chinese medicine ? TCM? syndromes of rheumatoid arthritis ? RA? by studying the Chinese medical patterns，and analyze the correlations of different indicators and related syndromes. Methods The questionnaires were designed according to clinical epidemiological theories. The data were collected and analyzed by multivariate statistical methods. Results The TCM symptoms of the 401 cases of RA were concluded into 3 common factors，that is，cold，heat and deficient. Their syndromes were sub-classified as 6 groups? cold syndrome，heat syndrome，deficiency，cold heat complex，deficient cold and asthenic fever. Statistical analysis showed that there were significant differences in health asses