About Premarin intravenous anesthesia combined with misoprostol treatment observation of 60 cases of missed abortion.docVIP

 PAGE \* MERGEFORMAT 8 About Premarin intravenous anesthesia combined with misoprostol treatment observation of 60 cases of missed abortion Missed abortion refers to death of embryo or fetus has not yet remaining in the uterine cavity by the natural discharge [1], can lead to tissue necrosis machine of, and close adhesion of the uterine wall, not easy to completely stripping, curettage can cause difficulties. Traditional treatment methods are often used Direct curettage. of the use of Premarin intravenous anesthesia combined with misoprostol treatment of 60 cases of missed abortion, and achieved good effect, are reported below. 1 Materials and Methods 1.1 Case selection conditions (1) age lt;40 years of age, (2) gestational age lt;16 weeks, (3) Palace is less than 12 weeks, (4) normal coagulation and liver function, (5) the uterus without organic diseases, (6 no misoprostol, propofol and ketamine medication contraindications, no drug allergies. 1.2 General Information Our hospital in June 2007 ~ June 2009 a total of 120 cases of missed abortion were treated, are in line with the above selected conditions. Randomly divided into observation group, 60 patients aged (24 + -8 years), gestational age 12 to 16 weeks, the control group 60 patients, age (25 + -6 years), gestational age 12 ~ l6 weeks .2 group of patients age, weight and the difference was not statistically significant (Pgt; 0.05, comparable. 1.3 Methods Observation group were treated with conjugated estrogen (brand name: Premarin, Wyeth Pharmaceuticals production, each piece of 0.625mg) 5mg, day 1. Continuous administration 3d, 4 days in the vagina or rectum after the vault misoprostol 400 ~ 600 μg, 2 ~ 4 h after administration of the experts painless curettage. preoperative fasting 4-6h, establishment of intravenous access, the implementation of intravenous anesthesia by the anesthesiologist. Anesthesia with propofol 2.5rag/kg bolus, bolus of ketamine 20-25rag. Contr