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Acute cerebral infarction and plasma homocysteine levels of correlation between NO
Study: Fan Hongbin, Wang Yi M, Zhu Ji-jun, Geng Deqin
[Abstract] of acute cerebral infarction of plasma homocysteine (Hcy) and nitric oxide (NO) levels and their correlation with acute cerebral infarction. Methods Using HPLC and Griess diazo reaction assay in patients with acute cerebral infarction in 62 cases (onset within 24 h) of plasma Hcy and NO levels, analysis of the correlation between its relationship with acute cerebral infarction. Results of acute cerebral infarction plasma Hcy levels were significantly higher than the control group (P lt;0.01), while the NO level was significantly lower than the control group (P lt;0.01). acute cerebral infarction group, the plasma Hcy level was negatively correlated with NO (r =- 0.904, P lt;0.01). Conclusions In acute brain Early infarction reduce the level of plasma NO, the reason may be before and after acute cerebral infarction related to high Hcy levels.
[Keywords:] Cerebral infarction; homocysteine; nitric oxide
Abstract: Objective To investigate the correlation between homocystine (Hcy) and nitric oxide (NO) in the blood plasma in patients suffering from acute cerebral infarction as well as their relationship with acute cerebral infarction.Methods 62 patients with acute cerebral infarction (within 24 hours ) were enrolled. High performance liquid chromatography (HPLC) and Griess diazotization reaction were employed to determine the levels of Hcy and NO in the plasma and the correlation between Hcy and NO was analyzed. Results The plasma levels of Hcy in acute cerebral infarction group were significantly higher than those in the healthy control group (P lt;0.01), whereas the NO levels were significantly lower (P lt;0.01). The of Hcy level was negatively correlated with the NO level (r =- 0.904, P lt;0.01). Conclusion During the early stage of acute cerebral infarction, the lower level of NO in
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