Advances in prevention and treatment of gout.docVIP

 PAGE \* MERGEFORMAT 14 Advances in prevention and treatment of gout Of: Li Zhongze, Deng Xiaoyan Yao Dehou [Keywords:] gout, uric acid, treatment Gout (Gout) purine metabolic disorder caused due to uric acid level is too high, and / or result in a decrease in uric acid excretion of urate deposition of tissue damage associated with a group of diseases. The main clinical manifestations, hyperuricemia, acute and chronic arthritis, renal failure, kidney stones, etc., but most people are found because of an acute arthritis. At present the diagnosis of acute gouty arthritis, multiple reference Association for the 1997 American College of Rheumatology classification criteria [1] may be. of high blood uric acid diagnostic criteria generally normal serum uric acid in 1980, the national survey mean, Mgt; = 420μmol / L, Fgt; = 360μmol / L. In recent years, domestic and international gout prevalence increased to 0.84% #8203;#8203;annually, the incidence rate of about 9.6% of the census [2,3]. Now younger than before onset, more severe disease severity [4]. The increase may be with the following factors: (1 certain diseases such as: obesity, metabolic syndrome, insulin resistance, hypertension, organ transplantation. (2 will increase the use of certain medications blood uric acid level. such as: diuretics, dehydration, low dose of salicylic acid used. (3 Census face deeper than before, or high to low population increase in areas such factors as immigration. (4 patients treatment too late, there has been renal insufficiency, in particular, the serum uric acid end-stage renal disease reduce exclusion, generating increased to more refractory gout [5]. It was proved that the blood uric acid level and after the first attack of gout incidence and age have a direct relationship between the [6]. At present there is no cure for gout, The purpose of the present treatment is timely control and reduce acute attack of gouty arthritis, uric acid levels to prevent urate depos