Analgesic anti-inflammatory ointment for treatment of phlebitis caused by amphotericin B efficacy.docVIP

 PAGE \* MERGEFORMAT 6 Analgesic anti-inflammatory ointment for treatment of phlebitis caused by amphotericin B efficacy Of: Ni Na, Li Ping, Yun Peng, Yan Rui [Abstract] Objective To observe the analgesic anti-inflammatory topical treatment with amphotericin B ointment phlebitis clinical efficacy. Methods 60 patients with intravenous amphotericin B result in phlebitis were randomly divided into treatment group and control group. The treatment group received anti-inflammatory pain relief cream topical in the vein at the control group, 50% magnesium sulfate at the external application in the vein, and then were observed local skin redness, pain, heartburn symptoms, and along the veins of the cord-like red line to the disappearance of clinical manifestations. Results There were local pain, swelling, comparing the statistical analysis, the difference was statistically significant (P lt;0.01). Conclusion The anti-inflammatory analgesic ointment topical treatment of phlebitis caused by amphotericin B is better than 50% of the efficacy of topical magnesium sulfate. [Keywords:] amphotericin B; phlebitis; analgesic anti-inflammatory ointment Polyene amphotericin B as antifungal agents, the treatment of severe fungal infection of the only effective drug, is widely used in clinical treatment of fungal infections, but amphotericin B toxicity, adverse reactions more common, multiple injections of easy cause phlebitis, which caused major clinical manifestations of phlebitis as local pain, extreme tenderness, along the blood vessels to cord-like swelling was. If treatment can not be effective in preventing the occurrence of phlebitis, will affect the patients continued treatment for the patient successfully complete the course, maintain good physical and mental condition, drug prevention and treatment of phlebitis occurred in clinical care workers is an important task. our department from January 2006 to March 2009 selection of analgesic anti-inflammatory topical