BNP after acute myocardial infarction and left ventricular remodeling and left ventricular function relationship of research.docVIP

 PAGE \* MERGEFORMAT 11 BNP after acute myocardial infarction and left ventricular remodeling and left ventricular function relationship of research Author: Wu Yue Zhang Guimin Yang Baihui [Abstract] acute myocardial infarction left ventricular remodeling after myocardial infarction lesion is an important pathophysiological process in which the brain natriuretic peptide (brain natriuretic peptide, BNP) in the development and progression of left ventricular remodeling plays an important role and with the heart functions are closely related. This article will discuss acute myocardial infarction (AMI) brain natriuretic peptide (BNP) level and post-infarction left ventricular remodeling and cardiac function were reviewed. [Keywords] BNP ventricular remodeling of left ventricular function Brain natriuretic peptide (brain natriuretic peptide, BNP) in 1988 by Japanese scholar Sudoh, etc. within the first isolated from porcine brain, the structure and function similar to the ANP as a natriuretic peptide. After the study found, BNP mainly by ventricular muscle cell synthesis and secretion, with the expansion of blood vessels, antagonize the renin - angiotensin - aldosterone system (RAAS), inhibition of sympathetic nerve activity, promote urinary sodium excretion, reduce the role of Shuinazhuliu The study confirmed that the hormone mainly reflects ventricular function. ventricular load and (or) wall tension increases, the rate of its synthesis and secretion of faster, ventricular dysfunction, as sensitive and specific biological indicators in recent years, changes in the secretion of BNP with a variety of cardiovascular diseases the relationship between the attention devoted to the cardiac function after myocardial infarction changes, BNP secretion and a significant increase in the severity and prognosis of its obvious relevance. 1 The biological characteristics of brain natriuretic peptide 1.1 BNP synthesis and secretion mainly by the ventricul