ICU Gram-negative bacilli resistance surveillance.docVIP

 PAGE \* MERGEFORMAT 8 ICU Gram-negative bacilli resistance surveillance [Keywords:] Gram-negative bacilli [Abstract] Objective To compare 2001 and 2004, two years I lived in ICU patients with hospital pathogens and bacterial resistance, and to explore treatment strategies for resistant infections. Methods Determination of hospitalized KB clinical isolates of drug sensitivity. The results in 2005 patients with ICU stay of the most common clinical isolates of Klebsiella (37.9%), Escherichia coli (25%), Pseudomonas aeruginosa (17%), Acinetobacter (8.4%) which ESBLS strains produced from 10% to 22%. Gram-negative bacilli infection in the numbers still have the edge. Imipenem, cefepime, cefoperazone - sulbactam and amikacin against gram-negative bacilli good antibacterial activity. Pseudomonas aeruginosa to imipenem, the resistance rate of Sulperazon slight decline, but rates of resistance to other antibiotics more than 42%. Sulperazon Klebsiella, imipenem still maintains a high degree of sensitivity, ESBLS producing strains resistant to quinolones rate was 62% or more. Escherichia coli to imipenem, piperacillin - tazobactam remain highly sensitive to ESBLS strains producing almost all the resistance to quinolones. Accounts for the first 4-bit to Acinetobacter-based and other non-fermentative bacteria strains isolated in 2001 the number decreased (from 27.3% to 8.4%) but its rate of various types of antibiotic resistance has increased . Conclusion Because of the widespread use of broad-spectrum antibiotics, Gram-negative bacilli resistant rate has undergone a significant change. Clinicians should pay attention to changes in bacterial resistance, rational use of antibiotics. [Keywords:] Gram-negative bacilli; resistance rate; antibacterial drugs As the antimicrobial agents in the treatment of infectious diseases has made the rapid development of a large number of widely used clinical antibiotic selection for antimicrobial agents cause bacterial resistance to s