Nursing of patients with organophosphate poisoning.doc

 PAGE \* MERGEFORMAT 7 Nursing of patients with organophosphate poisoning [Keywords:] organophosphate poisoning Organophosphate poisoning, its toxicity is mainly inhibited the activity of acetylcholinesterase, the organic phosphorus ester solution and the Ministry of acetylcholinesterase combine to form a stable phosphorylated cholinesterase, so that the large accumulation of acetylcholine in vivo and clinical poisoning on a corresponding performance of acute organophosphate poisoning such as first aid in a timely manner, restore the health of the majority of .2007 3 months to August, our hospital gastroenterology poisoning patients admitted to 23 cases, the active rescue and care, 21 patients 7 to 15 days in hospital were discharged and 2 patients gave up treatment because of his family, left the hospital. are summarized below. 1 Clinical data 1.1 General information on 23 patients, 15 males and 8 females; aged 12 to 56 years .19 cases of oral poisoning, 4 cases of pest control, the aspiration and sprinkle the skin of pesticide poisoning cases were in the 2 .21 within 5 h treatment, 2 patients taking the drug after the 7 ~ 12h treatment. 1.2 The group of 23 patients with symptoms and signs, have different degrees of miosis, unconsciousness, nausea, vomiting, incontinence. Laboratory tests on admission were 1.3 Jicha blood cholinesterase (ChE, 21 significantly lower ChE, ChE was normal in 2 cases. 1.4 First aid and treatment principles 1.4.1 General treatment for patients with dressing, if necessary, wash their shampoo and body surface, while gastric lavage be catheterization, to keep the airway clear, rational oxygen. 1.4.2 Drug treatment of early, adequate and repeated, continuous medication, to atropine, chloride (pralidoxime therapy. Atropinization as quickly as possible, while strictly controlling the amount of fluid and give diuretic, anti-inflammatory, liver protection, protect the brain cells to protect the gastric mucosa and