Patients with active pulmonary tuberculosis smear HRCT score and bacteriological and immunological correlation.docVIP

 PAGE \* MERGEFORMAT 15 Patients with active pulmonary tuberculosis smear HRCT score and bacteriological and immunological correlation [Abstract] Objective To investigate the HRCT scoring criteria in the diagnosis of active pulmonary tuberculosis. Methods 42 patients with sputum smear-positive tuberculosis patients, the HRCT examination and score, each side of the lung tissue is divided into into three areas, and all types of CT signs involving the scope of the score, analysis of score results and the results of bacteriological examination of sputum and peripheral blood levels of M. tuberculosis-specific IFN-γ correlation between. Results Based on the results of mycobacterial smears were divided into 4 groups, which, AFB (+12 cases, AFB (+ +11 cases, AFB (+ + +10 cases, AFB (++++ 9 cases, correlation analysis showed that (1HRCT total score with sputum-positive rating has a positive correlation (r = 0.9661 P lt;0.0001, (2HRCT total score with the TB antigens ESAT6, P4-6, P8.10-specific release of IFN-γ levels were positively correlated (r = 0.4805, P = 0.0017, r = 0.4451, P = 0.0083, r = 0.4211, P = 0.0131. Conclusions Patients with active tuberculosis CT signs of a complex range of standards-based HRCT score and bacteriology and immunology was positively correlated, indicating that the HRCT scoring criteria for clinical diagnosis and treatment and the therapeutic effects of guiding significance. [Keywords:] HRCT tuberculosis acid-fast bacilli staining of IFN-γ ELISPOT [Abstract] Objective To investigate the role of HRCT scanning scores in diagnosis of active pulmonary tuberculosis (PTB) patients. Methods 42 PTB patients that sputum smear were mycobacterium positivity were included into the study. Every lung field was divided into 3 zones. Extent to disease in each zone abnormalities was evaluated and summed to a HRCT score. The correlation between HRCT scores and release levels of specific IFN-γ in peripheral blood Bacillus tuberculosis as well as sput