Viral quasispecies profiles as the result of the interplay of competition and cooperation 英文论文文献.docVIP

Arbiza et al. BMC Evolutionary Biology 2010, 10:137 /1471-2148/10/137 RESEARCH ARTICLE Open Access Viral quasispecies profiles as the result of the Research article interplay of competition and cooperation Juan Arbiza1, Santiago Mirazo1 and Hugo Fort*2 Abstract Background: Viral quasispecies can be regarded as a swarm of genetically related mutants. A common approach employed to describe viral quasispecies is by means of the quasispecies equation (QE). However, a main criticism of QE is its lack of frequency-dependent selection. This can be overcome by an alternative formulation for th