肝动脉化疗栓塞联合门静脉持续灌注化疗治疗原发性肝癌的临床观察.pdfVIP

.409. 肚攘攘础与l临床 2圳9 年 10 月第 22 卷第5 期 肝动脉化疗栓寨联合门静脉持续灌注化疗 治疗原发性肝癌的临床观察 4提 林，周向荣，朱扣林，周盐风，浒劳芹，陈高阳，刘兴祥，何学率 (美耀市人民医院肿瘤科，江苏美耀 225500) 摘要:目的 探讨肝动脉化疗栓黎加门静脉持续激注化疗治疗原发性肝癌的l临床价值。方法 不能手术的原发性肝癌 82 例，随机 分成两缀，观察组以 TAC也 +PVC 怡疗，对照组单纯行 TACE 治疗，分别统计肿瘤大小、AFP、门静脉痛栓的变化以及 1 年生存来。编 果 两组治疗后总有效率:观察组 57.7% (15/26) ，对照组 30.4% (17/56) ，两组比较接异有统计学激义(P 0. 05); 治疗后 AFP 转 阴或滴度下降工分之…以上:观察组 77.8% (14/18) ，对照细 45.0% (1 8/40)( P 0.05) ; 1 年生存惑:观察组 65.4% (17/26) ， 对照 组 4 1. 1% (23/56) (P 0.05) 。结论 TAC览 +PVC 治疗版发性肝癌较局在姆 TACE 布更高的临床有效率。 关键询:原发性肝婚;肝动脉化疗检察;门静脉持续激注化疗 中图分类等:R735.7;R730.53 jt 献标识码:A 文章编号:1673 -5412(2∞9)05 -0409 -03 Clinical Value About Hepatic Arterial Chemoembolization and Portal Vein ContÍnuous Perfusion Chemotherapy in the Treatment of Primary Liver Cancer Cui Lin , Zhou Xiangrong , Zhu Koulin , Zhou Lanfe吨， You Fan阴阳. Chen Gaoyang , Liu Xingxiang , He Xuejun (Department 01 Oncology , Jiangyan People s Hospìtal.Jiangyαn 225500 ,China) Abstrad: ObJecttve To investig.幽 the clinicaI value about hepatíc arterial chemoembolization and portal veín conlinuou8 perfusíon chemo- therapy În the treatment of primary líver cancer. Methods 82 c刷刷 with inoperable primary liver cancer. They were randomly dívided ínto two groups: observation group with the treatment of TACE ~← PVC 10 TACE therapy alone a8 control group. Stalístícs were tumor size , AFP , portaI veÎn tumor thrombus , and one year survÎvaJ rale. Results The total effective rate of the two 伊Oups: 57.7% of the ob制rvation group (15瓜的， the contro1 group 30. 4% (17巧的， diff6rence between the Iwo group德 W!lS signi负cant (P 0.05) ; AFP negative after treatment , 。1 more than on• half decli