Clinical Efficacy and Toxicity of Anti-EGFR Therapy in Common Cancers英文文献资料.docVIP

HindawiPublishingCorporation JournalofOncology Volume2009,ArticleID567486,14pages doi:10.1155/2009/567486 ReviewArticle ClinicalEf?cacyandToxicityofAnti-EGFRTherapyin CommonCancers AmirHarandi,AishaS.Zaidi,AbigailM.Stocker,andDamianA.Laber DivisionofHematologyandMedicalOncology,J.G.BrownCancerCenter,UniversityofLouisville,Louisville,KY40202,USA CorrespondenceshouldbeaddressedtoAmirHarandi,amirharandimd@ Received26November2008;Accepted30January2009 RecommendedbyDanielChua Epidermalgrowthfactorreceptor(EGFR)isacellsurfacemoleculeandmemberoftheErbBfamilyofreceptortyrosinekinases. Itsactivationl