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Neglected Tropical Diseases, Neglected Data Sources, and Neglected Issues 英文参考文献
Viewpoint
NeglectedTropicalDiseases,NeglectedDataSources,
andNeglectedIssues
BurtonH.Singer1,2*,CarolD.Ryff2
1OfficeofPopulationResearch,PrincetonUniversity,Princeton,NewJersey,UnitedStatesofAmerica,2UniversityofWisconsin,Madison,Wisconsin,UnitedStatesof
America
Giventhebiomedicalrootsanddisease
treatment orientation of the Global Bur-
den of Disease (GBD) framework, as
exemplified in the World Bank’s 1993
World Development Report, Investing in
Health[1],itisnotsurprisingthatweareat
a crossroads where whole categories of
diseases and a new journal have the
adjective‘‘neglected’’intheirtitles.Some
of this neglect might have been avoided,
even at the outset, if the authors of the
1993 World Development Report had
paid attention to the contents of the
1992 World Development Report, which
neglecting, clean water and sanitation
projects, but unfortunately undertake no
follow-upevaluationofhealthconsequences
due to their minimal connection to the
healthsector[8,9].
harbored three or more parasites concur-
rentlyfromalistof12parasitesinvestigated
thatincludedfourhelminths(Ascarislumbri-
coides, hookworm, Schistosoma mansoni , and
Trichuristrichiura)andeightintestinalproto-
zoa,themostcommonbeingEntamoebacoli,
Theabovepreambleandareviewofthe
measurementissuesdiscussedbyMatherset
al.[7]pointtomultipleareasofneglect,and
thereby opportunities for improvement in
thefutureoftheGBDprogram.Wefocus
on three areas, namely (i) comorbidity,(ii)
theintegrationofhumanandanimalhealth
data, and (iii) enhancing data systems via
linkagestotheWorldTradeOrganization
(WTO).OurinvitationfromPLoSNeglected
TropicalDiseasestowriteaviewpointbased
on Mathers et al. [7] encouraged us to
criticallyevaluateformulationsoftheglobal
burden as expressed in disability-adjusted
life years (DALYs) lost, and a variety of
measurementproblemsconnectedwiththe
current GBD framework. Extensive cri-
tiquesoftheextantframeworkhavealready
appeared,manyofthemreferencedin[7].
Rather than repeating these critiques,
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