A New Classification of Prodrugs Regulatory Perspectives.docVIP

Pharmaceuticals 2009, 2, 77-81; doi:10.3390/ph2030077 OPEN ACCESS pharmaceuticals ISSN 1424-8247 /journal/pharmaceuticals Article A New Classification of Prodrugs: Regulatory Perspectives Kuei-Meng Wu Center for Drug Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, MD 20993, USA; E-Mail: kueimeng.wu@; Tel.: +1 301-796-9883 Received: 27 August 2009; in revised form: 25 September 2009 / Accepted: 9 October 2009 / Published: 14 October 2009 Abstract: Many therapeutic agents are manufactured and administered in prodrug forms. In this paper, a