A simple model based on mutation and selection explains trends in codon and amino-acid usage and GC composition within and across genomes.docVIP

/2001/2/4/research/0010.1 Research A simple model based on mutation and selection explains trends in codon and amino-acid usage and GC composition within and across genomes Robin D Knight, Stephen J reeland and Laura  Landweber Address: Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA. Correspondence: Laura  Landweber. E-mail: lfl@ Published: 22 March 2001 Received: 21 November 2000 Revised: 1 February 2001 Accepted: 13 February 2001 GenomeBiology 2001, 2(4):research0010.1–0010.13 The electronic version of this article is the complete one and c