Bench-to-bedside review Glucose and stress conditions in the intensive care unit.docVIP

Losser et al. Critical Care 2010,14:231 /content/14/4/231 REVIEW Bench-to-bedside review: Glucose and stress conditions in the intensive care unit Marie-Reine Losser , Charles Damoisel and Didier Payen * 1,2 1 1 Abstract The physiological response to blood glucose elevation is the pancreatic release of insulin, which blocks hepatic glucose production and release, and stimulates glucose uptake and storage in insulin-dependent tissues. When this ?rst regulatory level is overwhelmed (that is,