Blood transfusion during cardiac surgery is associated with inflammation and coagulation in the lung a case control study.docVIP

Tuinmanetal.CriticalCare2011,15:R59 /content/15/1/R59 RESEARCH OpenAccess Bloodtransfusionduringcardiacsurgeryis associatedwithinflammationandcoagulation inthelung:acasecontrolstudy PieterRTuinman1*,AlexanderPVlaar1,AlexanderDCornet4,JorritJHofstra1,MarcelLevi2,JoostCMMeijers3, AlbertusBeishuizen4,MarcusJSchultz1,ABJohanGroeneveld4,NicolePJuffermans1 Abstract Introduction:Bloodtransfusionisassociatedwithincreasedmorbidityandmortalityincardiacsurgerypatients, butcause-and-effectrelationsremainunknown.Wehypothesizedthatbloodtransfusionisassociatedwithchanges inpulmonaryandsystemicinflammationand