Botulinum Toxin Physiology in Focal Hand and Cranial Dystonia.docVIP

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Botulinum Toxin Physiology in Focal Hand and Cranial Dystonia.doc

Botulinum Toxin Physiology in Focal Hand and Cranial Dystonia

Toxins 2012, 4, 1404-1414; doi:10.3390/toxins4111404 OPEN ACCESS toxins ISSN 2072-6651 /journal/toxins Review Botulinum Toxin Physiology in Focal Hand and Cranial Dystonia Barbara Illowsky Karp National Institute of Neurological Disorders and Stroke, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA; E-Mail: karpb@; Tel.: +1-301-496-0150; Fax: +1-301-480-2983 Received: 3 September 2012; in revised form: 24 October 2012 / Accepted: 9 November 2012 / Published: 20 November 2012 Abstract: The safety and efficacy of botulinum toxin for the treatment of focal hand and

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