原创力文档Community transcriptomics reveals universal patterns of protein sequence conservation in natural microbial communities.docVIP
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Community transcriptomics reveals universal patterns of protein sequence conservation in natural microbial communities
Stewartetal.GenomeBiology2011,12:R26
/2011/12/3/R26
RESEARCH
OpenAccess
Communitytranscriptomicsrevealsuniversal
patternsofproteinsequenceconservationin
naturalmicrobialcommunities
FrankJStewart1,AdrianKSharma2,JessicaABryant2,JohnMEppley2andEdwardFDeLong2*
Abstract
Background:Combinedmetagenomicandmetatranscriptomicdatasetsmakeitpossibletostudythemolecular
evolutionofdiversemicrobialspeciesrecoveredfromtheirnativehabitats.Thelinkbetweengeneexpressionlevel
andsequenceconservationwasexaminedusingshotgunpyrosequencingofmicrobialcommunityDNAandRNA
fromdiversemarineenvironments,andfromforestsoil
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