Complement C3 serum levels in anorexia nervosa a potential biomarker for the severity of disease.docVIP

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Complement C3 serum levels in anorexia nervosa a potential biomarker for the severity of disease.doc

Complement C3 serum levels in anorexia nervosa a potential biomarker for the severity of disease

Flierletal.AnnalsofGeneralPsychiatry2011,10:16 /content/10/1/16 PRIMARY RESEARCH OpenAccess ComplementC3serumlevelsinanorexianervosa: apotentialbiomarkerfortheseverityofdisease? MichaelAFlierl1,JenniferLGaudiani2,AllisonLSabel3,4,CarlinSLong5,PhilipFStahel1,6 andPhilipS Mehler2,3* Abstract Background:Anorexianervosacarriesthehighestmortalityrateofanypsychiatricdisorder.Eventhemost criticallyillanorexicpatientsmaypresentwithnormal‘standard’laboratoryvalues,underscoringtheneedfora newsensitivebiomarker.Thecomplementcascade,amajorcomponentofinnateimmunity,representsadriving forceinthe

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