Complement C3 serum levels in anorexia nervosa a potential biomarker for the severity of disease.docVIP
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Complement C3 serum levels in anorexia nervosa a potential biomarker for the severity of disease
Flierletal.AnnalsofGeneralPsychiatry2011,10:16
/content/10/1/16
PRIMARY RESEARCH
OpenAccess
ComplementC3serumlevelsinanorexianervosa:
apotentialbiomarkerfortheseverityofdisease?
MichaelAFlierl1,JenniferLGaudiani2,AllisonLSabel3,4,CarlinSLong5,PhilipFStahel1,6 andPhilipS Mehler2,3*
Abstract
Background:Anorexianervosacarriesthehighestmortalityrateofanypsychiatricdisorder.Eventhemost
criticallyillanorexicpatientsmaypresentwithnormal‘standard’laboratoryvalues,underscoringtheneedfora
newsensitivebiomarker.Thecomplementcascade,amajorcomponentofinnateimmunity,representsadriving
forceinthe
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