原创力文档Comprehensive analysis of the genome transcriptome and proteome landscapes of three tumor cell lines.docVIP
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Comprehensive analysis of the genome transcriptome and proteome landscapes of three tumor cell lines
Akanetal.GenomeMedicine2012,4:86
/content/4/11/86
METHOD
OpenAccess
Comprehensiveanalysisofthegenome
transcriptomeandproteomelandscapesofthree
tumorcelllines
PelinAkan*,AndreyAlexeyenko,PaulIgorCostea,LiliaHedberg,BeataWerneSolnestam,SverkerLundin,
JimmieH?llman,EmmaLundberg,MathiasUhlénandJoakimLundeberg
Abstract
Weherepresentacomparativegenome,transcriptomeandfunctionalnetworkanalysisofthreehumancancercell
lines(A431,U251MGandU2OS),andinvestigatetheirrelationtoproteinexpression.Genecopynumbers
significantlyinfluencedcorrespondingtranscriptlevels;theireffectonproteinlevelswaslesspronounced.
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