强力宁合用丹参抗肝纤维化的疗效观察.PDFVIP

·116 · Chin J Clini Hep atol ,May 1999 ,Vol15 ,No 2 强力宁合用丹参抗肝纤维化的疗效观察 于忠省 　王玉刚　王铁军 　夏书泽 　常晓华 　赵秀兰 ( ) 　　【摘要】　本研究选择 72 例慢性乙型肝炎 CHB 病人 ,分强力宁加丹参组 、强力宁组 、丹参组 ( ) 及对照组 。治疗前后检测肝功能、病毒指标及肝纤维化血清学指标 HA 、PC Ⅲ,LN 及 IV - C 。结 果表明 ,治疗后肝纤维化指标均有不同程度好转 ,各治疗组与治疗前及对照组治疗后比较差异显 著 ,且强力宁与丹参联用抗肝纤维化作用优于单用强力宁或丹参 。 【关键词】　强力宁 　丹参 　慢性病毒性肝炎 　肝纤维化 The Clinical Effect of Potenlini( Glycyrrhizic Acid) and Salviae Miltiorrhizae f or Antif ibrosis 　 Yu Zhong S heng , Wang Yu Gang , Wang TieJ un , et al The Peop le Hosp ital of B in Zhou , 　2566 10 Abstract 　This study enrolled 72 p atient s wit h chronic hep atitis B (CHB) according to t he diagnos tic criteriaThey were divided into four grop s :potenlini and salviae miltiorrhizae ( SM) grop ( 20 p a tient s) ;potenlini group ( 18 p atient s) ; SM group ( 19 p atient s) and t he control group ( 15 p atient s) The liver function were proved in all group s , The serum p arameters of fibrosis all significantly changed after two or t hree treat ment duration in treated group sThe result s showed t hat potenlini and SM bot h had t he effect of antifibrosis and t he combination of t hem can promoto t he effect of antifibrosis Key Words 　Potenlini ( Glycyrrhizic Acid) 　Salviae miltiorrhizae 　Chronic viral hep atitis 　Liver fibrosis ( ) 　　肝纤维化是慢性肝病的重要病理改变 , 12 　治疗方法 :72 例病人随机分为 1 : 强 肝纤维化的发展与肝病的进展及预后有密切 ( ) ( ) ( 力宁 + 丹参组 20 例 , 2 : 强力宁组